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At the cellular level, ferroptosis is triggered by the inhibition of cell membrane translocation factors such as cystine/glutamate translocator (also known as the system Xc-) or the activation of transferrins, as well as the blockade of intracellular antioxidant enzymes such as glutathione peroxidase 4 (GPX4) (3, 9)

Serum iron levels and tissue non-heme iron concentrations were determined

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The active sites of each SOD subunit has a metal cluster made up of atoms of copper and zinc connected by a histamine residue